Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines.
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چکیده
منابع مشابه
Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines
Subtractive hybridization, selecting for mRNAs expressed in normal human mammary epithelial cells (NMECs) but not in mammary tumor cell lines (TMECs), led to the cloning of the human gap junction gene connexin 26 (Cx26), identified by its sequence similarity to the rat gene. Two Cx26 transcripts derived from a single gene are expressed in NMECs but neither is expressed in a series of TMECs. Nor...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1992
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.118.5.1213